POS88 SLOT FUNDAMENTALS EXPLAINED

To study the effect of a number of constraints on mutational tolerance all through collection, we chose E. coli dihydrofolate reductase (DHFR) like a model system. DHFR is an essential enzyme inside of folate metabolism that lessens dihydrofolate to tetrahydrofolate and is particularly necessary for thymidine output. working with this exercise as T